Archiv nach Monat:: April 2026

Introduction: Generalized myasthenia gravis (gMG) may progress to life-threatening myasthenic crises (MC) requiring mechanical ventilation. Standard therapy includes intravenous immunoglobulins (IVIg), plasmapheresis (PLEX), immunoadsorption (IA), and high-dose corticosteroids. This study aimed to evaluate the real-world effectiveness of complement-inhibitors (C5-I) in patients refractory to the standard treatment of MC (termed therapy-refractory MC). Methods: This multicentre, retrospective… Read more »

Background: Multiple sclerosis (MS) is a chronic disease affecting the central nervous system. People with MS (PwMS) have a strong need for lifestyle-related information, and their motivation to change dietary behaviour is typically high. A recent randomised controlled trial showed that the digital health application (DiGA) levidex led to an increase in diet quality in… Read more »

Intermittent hypoxia intervention may provide an alternative therapeutic approach to enhance neuroprotection in people with multiple sclerosis (pwMS). However, clinical data on its safety and feasibility in pwMS are lacking. In this prospective single-arm safety and feasibility trial, individuals with primarily progressive MS (18-60 years; Expanded Disability Status Scale ≤6.5) were recruited from the MS… Read more »