Manuel A. Friese studied medicine at the Universities of Hamburg, Oxford and University College London and received his MD in 2001. He completed his neurology training at the Universities of Tübingen and Hamburg. After his postdoctoral training at the University of Oxford from 2004––2008, he started his laboratory as an Emmy Noether research fellow of the Deutsche Forschungsgemeinschaft at the University of Hamburg. Since 2013 he has been consultant neurologist and Professor of Neuroimmunology at the University of Hamburg and since 2014 director of the INIMS. His laboratory focuses on inflammatory and neurodegenerative aspects of neuroimmunological and neuroinfectious diseases.

Christoph Heesen studied medicine at the Universities of Marburg and Kiel and received his MD in 1993. He completed his neurology training at the General Hospital in Bremen –Ost and the Univeristy Medical Centre Hamburg-Eppendorf. Since 1995 he is head of the MS outpatient unit and since 2004, he has been consultant neurologist. He was deputy director of the Institute of Neuroimmunology and Clinical MS Research (INIMS) from 2006–2010. In 2017 he became an endowed professor of clinical and rehabilitative MS research at the INIMS. His research focusses on behavioural interventions and strategies to enhance patient autonomy with a special interest in Ehealth interventions.

Sina C. Rosenkranz studied medicine at the Universities of Hamburg, Berlin, Zürich, Pretoria and Campeche and started her residency in 2012 at the Department of Neurology at the University Medical Centre Hamburg-Eppendorf by focusing on Neuroimmunology. After completing her MD thesis at the Institute of Neuropathology on Alzheimer‘s disease she enrolled in the MD/PhD programme of the UKE where she investigated the role of mitochondrial alterations during Multiple Sclerosis. Currently she is working on the molecular basis of neuroprotective behavioural interventions, such as exercise and hypoxia. She is one of four fellows of the Hertie Network of Excellence in Clinical Neuroscience.

As administrative assistant of the MS Outpatient Clinic, Marile Miara supports the clinical team realising clinical research projects, e.g. registration at ethical review committees and contracts. Accordingly, she organises correspondence and meetings and assists in all administrative aspects regarding personnel, clinical case management, financial and purchase matters.

As administrative assistant, Bärbel Reimers supports the director and researchers of the INIMS in realising their research and clinical projects. In accordance she organises correspondence and meetings and assists in all administrative aspects regarding personnel, financial and purchase matters. Since 2019 she has been involved in the training of office management assistants.

Manuel A. Friese studied medicine at the Universities of Hamburg, Oxford and University College London and received his MD in 2001. He completed his neurology training at the Universities of Tübingen and Hamburg. After his postdoctoral training at the University of Oxford from 2004––2008, he started his laboratory as an Emmy Noether research fellow of the Deutsche Forschungsgemeinschaft at the University of Hamburg. Since 2013 he has been consultant neurologist and Professor of Neuroimmunology at the University of Hamburg and since 2014 director of the INIMS. His laboratory focuses on inflammatory and neurodegenerative aspects of neuroimmunological and neuroinfectious diseases.

As administrative assistant, Bärbel Reimers supports the director and researchers of the INIMS in realising their research and clinical projects. In accordance she organises correspondence and meetings and assists in all administrative aspects regarding personnel, financial and purchase matters. Since 2019 she has been involved in the training of office management assistants.

Jan Broder Engler studied medicine at the Charité Berlin and the University of Córdoba in Spain. Fascinated by how immune responses are regulated, he joined the Group of Cell Autoimmunity at the German Rheumatism Research Centre Berlin (DRFZ) and received his MD for his work on autoreactive T cells in lupus in 2010. For gaining deeper mechanistic understanding of how immune tolerance can be restored, he joined the INIMS in 2011 and received his PhD of Human Biology in 2015 and the Dr. Martini Prize 2018 for his work on mechanisms of pregnancy-induced immune tolerance. Driven to identify genuine neuroprotective treatment strategies, Broder switched to neurobiology and systems biology to understand how neurons cope with inflammation. In 2020 he became a fellow in the Hertie Network of Excellence in Clinical Neuroscience and in 2021 a Senior Scientist at the INIMS. Currently, Broder explores genetic and epigenetic treatment strategies to empower neurons to fight back inflammation.

Anne Willing studied biology and biomedical sciences at the University of Münster and the transnational University Limburg (Netherlands/ Belgium). From 2009 to 2013 she completed her PhD study characterizing IL-17 producing CD8+ T cells in multiple sclerosis at the INIMS. Her main research focus is T cell and particularly MAIT cell biology in the context of immunological pathomechanisms of multiple sclerosis. In 2021 she received DFG funding to decipher the role of MAIT cells in MS and its mouse model and became Senior Scientist. In addition to her own research activities, she is Scientific Coordinator at the INIMS since 2017 supporting co-operative research projects and teaching activities, as well as co-ordinating biobanking at the INIMS.

Lars Binkle studied biology at the Freie Universität Berlin. For his PhD he joined the Institute for Molecular and Cellular Cognition (IMCC) at the Center for Molecular Neurobiology Hamburg (ZMNH) and received his PhD (Dr. rer. nat.) in 2010. In 2011 he became a postdoctoral fellow at the IMCC studying the molecular function of the immediate early gene Arc/Arg3.1, a master regulator of synaptic plasticity and cognition. In 2017 he became a postdoctoral fellow at the INIMS. His main research focus is the TRPM4 CAN channel and its protective function in neurodegeneration. In cooperation with biotech companies, he advances the development of TRMP4 inhibiting drugs that can be used in the treatment of multiple sclerosis.

Inbal studied Biotechnology and Food Engineering at the Technion in Haifa (Israel) and completed her master’s degree in cell biology at the faculty of biology at the Technion in 2012. Following that, Inbal started her PhD studies at the Max Delbrück Center for Molecular Medicine in Berlin, where she investigated structural determinants and regulators that govern the proteolytic fate of the NF-κB precursors p100 and p105. Subsequent to the completion of her PhD in 2018, Inbal joined INIMS as a postdoctoral researcher. Her main research focus is neuronal aggresome formation as driver of neurodegeneration in multiple sclerosis.

Fernando Lucas Ruiz studied the Biochemistry Bachelor degree at the University of Murcia. From 2015 to 2020 he completed his PhD in the Experimental Ophthalmology group at the University of Murcia, focusing on the study of the neurodegenerative and neuroinflammatory processes of retinal ganglion cells after the optic nerve axotomy. In 2021 he joined the Molecular Inflammation group at the Biomedical Research Institute of Murcia, where he investigated the mechanisms of pyroptosis activation through the NLRP3 inflammasome. Since 2022 he is part of the INIMS and his research focuses on uncovering the neuronal death pathways that occur in MS, as well as on the study of the neurodegenerative processes that occur in the retina during MS disease.

Jana Sonner studied Molecular Biotechnology at the University of Heidelberg until 2014 and completed her PhD studies in 2017. From 2014 to 2019 she worked in the Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology at the German Cancer Research Center (DKFZ) in Heidelberg, where she dissected the role of tryptophan metabolism in regulation immune responses in experimental models of multiple sclerosis, glioma and melanoma. In March 2019 she joined the INIMS as a postdoctoral scientist and is now working on the phenomenon of natural immune tolerance induction during pregnancy, which modulates disease activity in autoimmune neuroinflammation. In addition, she is developing a platform to identify novel potential targets for MS therapy using systems biology approaches.

Mark Walkenhorst studied Bioscience at the Westfälische Wilhelms-University Münster and received his masters degree in 2015. He joined the INIMS as a PhD student in 2016 and completed his PhD on the role of mucosal-associated invariant T (MAIT) cells in the animal model of multiple sclerosis in 2020. He is now continuing his work on MAIT cells in the pathogenesis of central nervous system inflammation as a postdoctoral scientist.

Iris Winkler started her studies in English and Biology at Bergische University of Wuppertal. Discovering her fascination of how the central nervous system (CNS) works, she intensified her studies at Ruhr-University of Bochum with focus on neurobiology. Within her bachelor thesis she explored the regulation and function of a neuropeptide in migraine and during her master thesis she manipulated neuronal network activity by application of optogenetic tools. During her master’s module neuroimmunology she ascertained her interest in neurological disorders associated with CNS inflammation, which brought her to work on understanding neurodegenerative pathways in multiple sclerosis (MS) at the INIMS in 2015. During her PhD she investigated the functional role of regulatory small RNAs (microRNAs) to understand how neurons buffer environmental contingencies caused by CNS inflammation. In her current work she continues studying microRNA–mRNA networks in order to reveal new protective neuron intrinsic pathways in MS.

Felix Fischbach studied medicine at the Ludwig-Maximilian’s University of Munich (LMU). Fascinated by the complex interactions of glial cells and neurons in a neuroinflammatory condition he carried out his MD thesis in the Department of Neuroanatomy in Munich investigating oligodendroglial stress responses in inflammatory and metabolic animal models of Multiple Sclerosis. In April 2020 he started his residency at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE). Since the middle of 2021, he works as a postdoctoral scientist at the INIMS. He continued his research at the INIMS and focusses on cellular stress responses of neurons in an inflammatory environment, especially those involving protein accumulation. Additionally, he is interested in neurodegeneration not being driven by inflammation and the associated glial responses.

Alexandros Hadjilaou studied medicine at the University of Leipzig. From 2012 to 2014 he worked on the immunology of the dengue fever at the Virology Department of the University of Leipzig and of the University of California, Berkeley (UCB) under the supervision of Christian Jassoy and Eva Harris respectively. His work, which culminated in his MD thesis in 2017, focused on developing the Quad-Color FluoroSpot (QCF) to characterise the antibody repertoire of B cells generated following a dengue virus (DENV) infection. Driven by the fascinating and captivating complexity of neurological diseases, which interests him to the same extent as infectious diseases, he is currently pursuing his residency in clinical neurology at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE). To merge his interests in clinical medicine and biomedical research, he works as a postdoctoral scientist at the INIMS and enrols in the MD/PhD programme. In his PhD thesis, he aims to broaden our understanding of the role of the brains endothelium in the pathogenesis of cerebral malaria. He is also interested in the pathogenesis, diagnosis and treatment of meningoencephalitides of infectious or unknown origin.

As a strong believer in the transformational power of digitalisation, Max Kaufmann investigates molecular disease mechanisms of multiple sclerosis using a high-throughput, data-driven approach. By treating patients as a physician and observing the current limitations of available medicines first-hand, he draws great motivation to extend beyond these boundaries with his research. Dr. Kaufmann’s scientific work has been funded by the German Cancer Aid (Mildred Scheel Scholarship), the Stifterverband (MS Clinician Scientist Programme) and the German Research Foundation (Walter Benjamin Programme). He is a postdoctoral scientist at the INIMS since 2016 in the group of Prof. Friese and has close ties to the Oxford Centre for Neuroinflammation (Prof. Fugger), where he worked as a visiting postdoc in 2021.

Christina Mayer obtained her medical degree from the University of Heidelberg and trained at Karolinska Institute in Stockholm and University College London. Fascinated by the fine-tuned interplay between immune cells and neurons, she carried out her MD thesis in the Department of Neurology in Heidelberg investigating neurodegenerative alterations in retinal ganglion cells during onset of autoimmune optic neuritis in an animal model of Multiple Sclerosis. She started her residency in the Department of Neurology at the University Medical Centre Hamburg-Eppendorf in 2019. Since the beginning of 2020, she works as a postdoctoral scientist at the INIMS and enrols in the Clinician-Scientist in Multiple Sclerosis research programme. Her research will focus on cell-type specific susceptibility for inflammation-induced neurodegeneration using the retina as a model system with good in vivo accessibility.

Lena Kristina Pfeffer studied medicine at the Technical University of Munich (TUM) and trained at the University of Zurich (UZH) and at the University College London (UCL). She carried out her MD thesis at the Institute of Clinical Neuroimmunology (Ludwig Maximilian University of Munich, LMU) studying the role of autoantibodies in Multiple Sclerosis. In 2020, she began her residency at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE). Since November 2021, she works as a postdoctoral scientist at the INIMS and is enrolled in the Clinician Scientist Program of the DFG Research Unit 5068 “Sex differences in immunity“. Her research focuses on sex differences in T-cell-mediated autoimmunity in Multiple Sclerosis and experimental autoimmune encephalomyelitis (EAE). Additionally, she is interested in the pathophysiology and treatment of Autoimmune Encephalitis and contributes to the German Network for Research on Autoimmune Encephalitis (GENERATE).

Charlotte Schubert studied medicine at the Universities of Freiburg im Breisgau, Marseille and Paris. Fascinated by the complexity of neurobiology she carried out her thesis on neuroplasticity through 2-Photon long-term in vivo imaging in a model of epilepsy. In 2017 she started her residency at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE) with a wide clinical interest in neuroimmunology, neurodegeneration and epilepsy. In 2018 she became a research fellow at the INIMS and joined the Collaborative Research Center “Adenine Nucleotides in Immunity and Inflammation” (CRC 1328). Her research focuses on pathophysiological mechanisms that drive inflammation-induced neurodegeneration in the experimental autoimmune encephalomyelitis (EAE) and Multiple Sclerosis in particular in the olfactory bulb and investigates possible neuroprotective treatment strategies via purinergic signaling.

Marcel S. Woo studied medicine at the University Medical Centre Hamburg-Eppendorf (UKE) and was additionally trained in computational neuroscience in the Montreal Neurological Istitute (Montreal, Canada). He carried out his MD thesis on the impact of metabotropic glutamate receptors and neuronal calcium and cAMP signalling on inflammatory neurodegeneration at the INIMS (Hamburg, Germany). At the beginning of 2021 he began his residency at the Department of Neurology at the University Medical Center Hamburg-Eppendorf (UKE). He continued his research at the INIMS and focusses on identifying new therapeutic strategies to counteract neurodegeneration in MS. Therefore, he combines bioinformatics and molecular cell biology approaches and analyses dysregulated neuronal transport and signalling in an inflammatory environment. Additionally, he is interested in systemic biology and evolutionary medicine to delineate the physiologic and pathologic adaptation to infection, inflammation and autoimmunity. He is funded by the Hertie-Stiftung and Werner-Otto-Stiftung.

I have studied the 'International master: from fundamental molecular biosciences to biotherapies ' at Sorbonne Universite - Pierre et Marie-Curie, gratuating in June 2021. During my master, I first investigated stem cells regeneration in an inflammatory context (Instituto de Medicina Molecular, Lisboa). Further on, I did my master thesis looking at the role of a hematopoietic marker in T-cells in Acute Lymphoid Leukemia (APHP Saint-Antoine Hospital Paris, Sorbonne Universite). As I have a great interest in sex and gender-sensitive biomedical research, I have decided to pursue a PhD focusing on women's health and started at the INIMS in October 2022. I will be focusing on the investigation of T-cell function and their modulation by pregnancy and its implications for the pathogenesis of Multiple Sclerosis and its animal model (Experimental Autoimmune Encephalomyelitis: EAE). I would also like to learn to conduct biomedical research taking into account sex and gender in experiments set-up and data analysis. On the other hand, I want to develop a program to promote and empower women scientists in their careers, and help with intersectionality issues in research.

Lisa Unger studied pharmacy at the Technical University of Braunschweig until 2016 and completed her master degree in biology with focus on molecular biology and biotechnology at the University of Hamburg in 2020. She started her PhD at the INIMS in october 2020 and will be equipping neurons to fight back inflammation and investigate resulting neuroprotective effects in the context of multiple sclerosis.

Ingo Winschel studied pharmacy at the Westfälische Wilhelms-University Münster and started his PhD at the INIMS in 2017. He is part of a research project funded by the DFG focusing on the sexual dimorphism in the immune system. For his PhD thesis, he is investigating sex-specific differences in the pathogenesis of multiple sclerosis mainly focusing on differentially expressed genes between the sexes and their functional influence on immune cell function.

Maximilian Anschlag is currently studying medicine at the University Medical Center Hamburg-Eppendorf (UKE). He started his MD thesis at the INIMS in October 2022 and will investigate the formation and composition of neurotoxic aggregates of the presynaptic protein Bassoon in multiple sclerosis.

Lukas Bal is currently studying medicine at the University Medical Center Hamburg-Eppendorf (UKE). He started his MD thesis at the INIMS in October 2018 and will investigate the role of neuronal microRNA-155 in inflammation-induced neurodegeneration.

Phaidon Christodoulou is a medical student at the University Medical Center Hamburg-Eppendorf (UKE). He started his MD thesis at the INIMS in October 2022 and aims to understand the mechanisms that drive T-cell mediated immunopathology in cerebral malaria.

Henrike completed her medical studies at the university of Freiburg in 2022. Due to her interest for neuroimmunology she joined the INIMS in November 2022 to investigate the role of ApoL6 in the defense against viral neuroinfection and in cell toxicity.

Hannah Maria Hagemeyer is currently studying medicine at the University Medical Center Hamburg-Eppendorf (UKE). She started as clinical research fellow at the INIMS in 2020 and investigates the role of ApoL6 in viral and autoimmune neuroinflammation.

Ricardo Lopes Fonseca is currently studying medicine at the University Medical Center Hamburg-Eppendorf (UKE). He started his MD thesis at the INIMS in April 2021 and will investigate the role of purinergic signaling and the potential neuroprotective effects in experimental autoimmune encephalomyelitis (EAE).

Julia von Grebmer is a medical student at the University Medical Center Hamburg-Eppendorf (UKE). She started her MD thesis at the INIMS in October 2022 and is investigating the role of adenosine kinase (ADK) and its isoforms in modulating inflammation-induced neurodegeneration.  

Simone Bauer has been working in the INIMS lab since 2011 as a technical assistant, where she is involved in several neurobiological and immunological projects. Besides genotyping and lab organization she is trained in the preparation of immune cells from different tissues including the inflamed CNS, isolation and culture of bone marrow derived dendritic cells, setup of stainings for flow cytometry and various primary cell culture systems.

Nina Meurs joined the INIMS in 2011 as a technical assistant in the Friese lab, and since she is involved in different neurobiological and immunological projects. Besides lab organization and mouse preparations, such as ZNS, lymph nodes or spleen preparations, her main area of expertise comprises 10X single cell experiments, flow cytometry including cell sorting as well as processing of human blood samples. Furthermore, she is responsible for the organisation and database of the internal biobank.

Stefanie Reinhardt has been working in the INIMS laboratory since 2007 as a technical assistant. Furthermore, she is a trained study nurse involved in Investigator Initiated Trials conducted by the multiple sclerosis outpatient clinic, i.e. investigating therapeutic effects of autologous hematopoietic stem cell transplantation or boswellia serrata in multiple sclerosis.

Vanessa Vieira joined the INIMS lab in 2017 as a technical assistant. In addition to lab organization and the processing of blood samples for the Biobank she has also been involved in several neurological projects. Her expertise lies in mouse CNS preparations and in methods such as BacTRAP and 10X single cell experiments.

Sina C. Rosenkranz studied medicine at the Universities of Hamburg, Berlin, Zürich, Pretoria and Campeche and started her residency in 2012 at the Department of Neurology at the University Medical Centre Hamburg-Eppendorf by focusing on Neuroimmunology. After completing her MD thesis at the Institute of Neuropathology on Alzheimer‘s disease she enrolled in the MD/PhD programme of the UKE where she investigated the role of mitochondrial alterations during Multiple Sclerosis. Currently she is working on the molecular basis of neuroprotective behavioural interventions, such as exercise and hypoxia. She is one of four fellows of the Hertie Network of Excellence in Clinical Neuroscience.

Jasmina Bier studied Medicinal Chemistry and Chemical Biology at the Jacobs University in Bremen and completed her master degree in Neurosciences at the University of Göttingen in 2020. She started her PhD at the INIMS in 2021 and will investigate neuroprotective strategies in multiple sclerosis such as exercise and hypoxia.

Daniela Silva studied Biochemistry at the University of Porto, and completed her master ‘s degree in Neurobiology at the University of Porto, Faculty of Medicine in 2022. During her degrees she enrolled in different projects, such as searching for miRNAs as potential biomarkers for MS and searching for potential beneficial effects of different repurposed drugs on preterm hypoxia ischemia injury. In July 2023 she joined the INIMS as a PhD student and aims to investigate the role of neuroinflammation on epigenetic changes upon neurogenesis and possible therapeutic approaches to improve MS outcomes.

Lena Sophie Niehoff is currently studying medicine at the University Medical Center Hamburg-Eppendorf (UKE). She started her MD thesis at the INIMS in April 2022 and will investigate the changes in neurogenesis in experimental autoimmune encephalomyelitis (EAE) and possible therapeutic approaches to improve the development of new neurons in the adult brain.

Christoph Heesen studied medicine at the Universities of Marburg and Kiel and received his MD in 1993. He completed his neurology training at the General Hospital in Bremen –Ost and the Univeristy Medical Centre Hamburg-Eppendorf. Since 1995 he is head of the MS outpatient unit and since 2004, he has been consultant neurologist. He was deputy director of the Institute of Neuroimmunology and Clinical MS Research (INIMS) from 2006–2010. In 2017 he became an endowed professor of clinical and rehabilitative MS research at the INIMS. His research focusses on behavioural interventions and strategies to enhance patient autonomy with a special interest in Ehealth interventions.

Stefan Gold studied psychology in Giessen and Hamburg and received his PhD from the University of Hamburg in 2003. He completed postdoctoral training in neuroimaging at New York University (NYU) and in neuroimmunology at the University of California Los Angeles (UCLA). Stefan is a guest scientist at the INIMS and Heisenberg Professor of Neuropsychiatry at Charité Universitätsmedizin Berlin. He is interested in neuro-endocrine-immune regulation and its role in the pathogenesis of autoimmune and psychiatric disorders. His lab employs techniques from molecular biology, immunology, endocrinology, neuroimaging, and neuropsychology to study biological mechanisms of disease progression and neuropsychiatric symptoms in MS and other chronic disorders.

As administrative assistant of the MS Outpatient Clinic, Marile Miara supports the clinical team realising clinical research projects, e.g. registration at ethical review committees and contracts. Accordingly, she organises correspondence and meetings and assists in all administrative aspects regarding personnel, clinical case management, financial and purchase matters.

Jana Pöttgen studied psychology at the University of Hamburg and received her diploma in 2009. Since 2006 she is engaged in neuropsychological assessments and neuropsychiatric research in multiple sclerosis at the MS Day Hospital and INIMS. She is interested in cognitive behavioral interventions in multiple sclerosis and the development and validation of neuropsychiatric outcome parameter. She received her PhD on “Metacognitive and allday live relevant training for people with MS – Development and pilot study of a cognitive program to treat neuropsychiatric impairment in MS”. She currently develops training programs to treat specific neuropsychiatric impairment in multiple sclerosis (e.g. depression, fatigue, social cognition), and is involved in the development and research of online treatment of neuropsychiatric domains in multiple sclerosis as depression but also of fatigue.

Karin Riemann-Lorenz studied nutritional sciences in Gießen and Mönchengladbach and got her diploma in 1991. She has been working as a freelance nutritionist, in adult education and as a nutrition expert for a consumer organization. In addition to her professional activity, she has completed master's degrees in Adult Education and Public Health. Since 2016, she has been a member of the Heesen Group at the INIMS and completed her PhD about lifestyle management for persons with MS in 2020. Her research focus is on the potential influence of health behaviours on MS disease course and the development of evidence-based patient information and behaviour change interventions for persons with MS.

Vivien Häußler studied medicine at the Universities of Hamburg and Trondheim and started her residency in 2013 at the Department of Neurology at the University Medical Centre Hamburg-Eppendorf. She completed her MD thesis in the area of postischaemic inflammation and first focused on basic science in the context of ischaemic stroke. Her clinical interests lie in the field of neuroimmunology and in 2018 she joined the INIMS becoming a clinical research fellow as well as working in the MS day hospital and outpatient clinic. Her scientific aims address the natural history of MS and NMO with a special focus on prognostic criteria and treatment response and she is in charge of clinical MS cohorts and the German NMO register NEMOS at our center.

Insa Schiffmann studied Medicine at the University of Freiburg and Sevilla and started her residency in 2017 at the MS day hospital and outpatient clinic of the University Medical Center Hamburg Eppendorf (UKE). In her thesis she examined the effects of epigenetic drugs on histone modifications in Non-small cell lung cancer. She is a member of the research team of Prof. Heesen focusing on evidence-based medicine and patient information in MS.

Pauline Gerschwitz studied psychology at Kiel University and graduated with a master's degree in 2021. From 2020 to 2021, she worked as a student trainee in neuropsychological research at the MS Day Clinic and INIMS. As part of her master's thesis, she developed a metacognitive questionnaire for people with multiple sclerosis and depressive symptoms. After completing her master's degree in 2021, she began her licensure training as a child and adolescent psychotherapist with a focus on cognitive and behavioral therapy. As part of this, she worked as a psychologist in a medical care center and child and adolescent psychiatry with a focus on depression in adolescence. In 2023, she began working as a research assistant in neuropsychological assessment and research in multiple sclerosis at the MS Day Clinic in a project supporting GAIA's digital health applications targeting depression, fatigue, anxiety and lifestyle in people with multiple sclerosis.

Alex Maximilian Keller studied "Health promotion and management" (B.A.) at the University of Applied Sciences in Magdeburg and completed his M.Sc. in "Health Sciences" at the University of Applied Sciences (HAW) in Hamburg. He has been working as a PhD student at INIMS since early 2023, where he is conducting research on lifestyle interventions for people with multiple sclerosis. Specifically, his focus is on investigating the barriers and resources that impact smoking cessation.

Nicole Krause studied Health Sciences (M.Sc.) at the Hamburg University of Applied Sciences (HAW Hamburg) and received her master‘s degree in 2018. After her studies, she was working as a research assistant at the HAW. She is working as a PhD student at the INIMS of the University Medical Center Hamburg-Eppendorf (UKE) since October 2018. As a member of the ‘Heesen Group’, she is investigating the influence of a web-based behavioural intervention on the inflammatory disease process in early multiple sclerosis patients.

Susan Seddiq Zai studied psychology at the University of Kiel and received her diploma in 2019. Since 2017 she is engaged in neuropsychological assessments and neuropsychiatric research in multiple sclerosis at the MS Day Hospital and INIMS. Currently, she is working as a PhD student on a project aiming to validate a driving simulator for patients with multiple sclerosis.

Stephanie Lau studied education at the University of Cologne. After her degree she completed a journalism traineeship and worked as a journalist for several TV stations. Since 2010, she has been working in the MS Outpatient Clinic, mainly in charge of neuropsychiatric assesments and the development and realisation of educational research projects for MS patients. In addition, she councels patients in the context of our DECIMS-Project (Decision Coaching in MS).

Barbara von Glasenapp has been recruited for the POWER@MS1 project in August 2021. She has a Bachelor of Science degree in Physiotherapy and is a certified paramedic assistant. Previously she worked as a physiotherapist in field of epilepsy. She assists the Power@MS1 project and other clinical trials.

Heike Ellerich has been recruited for the POWER@MS research project at the multiple sclerosis out patient clinic in April 2019. She is a qualified medical assistent and study nurse. She is responsable for the imaging data of prospective cohorts, RCTs and fMRI task acquisition. Furthermore she takes care of the German NMO register NEMOS and assists in other clinical trials.

Since 2008 Kristina Grentzenberg has been working in the multiple sclerosis day clinic. She is a qualified nurse for intensive care and a study nurse. She coordinates the day clinic and is involved in patient education programmes, specifically the DECIMS (Decision Coach in MS)-project.

Since 1998 Andrea has been working at the multiple sclerosis out patient clinic and was involved in setting up the structures of the clinic. She is a qualified nurse and as a study nurse is responsible for most of the multicenter phase 2 and 3 clinical trials.

Since December 2021 Julia Balser is working at the multiple sclerosis out patient clinic. Her main function is the admission of patients and to enter patient-related data into the Hospital System. She maintains the MS Patient Database and is responsible for the correspondence between doctors and patients. Julia Balser also supports the infusion therapy of patients in the MS outpatient unit.

Since December 2022 Masoumeh Bonari is working at the multiple sclerosis out patient clinic. Her main function is the admission of patients and to enter patient-related data into the Hospital System. She maintains the MS Patient Database and is responsible for the correspondence between doctors and patients.

Since 2009 Sabine Nagel has been working in the multiple sclerosis out patient clinic. She is a qualified administrative assistant in public service. Her main function is the admission of patients and to enter patient-related data into the hospital system. She also coordinates the day clinic.