Comparison of anti-human T cell globulins on immune reconstitution and early infections after autologous transplant in patients with multiple sclerosis.

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Autologous hematopoietic stem cell transplantation is an effective therapeutic option for patients with treatment-refractory multiple sclerosis (MS) and may be considered as first line treatment in aggressive forms. Currently, a variety of conditioning and serotherapy regimens are employed across transplant centers. In this study, we compared immune reconstitution at days 30 and 100 post-transplant in… Read more »

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis.

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Purpose: To explore the relationship between visual performance and retinal morphology as assessed by optical coherence tomography (OCT), and the ability of OCT to reflect visual impairment in people with multiple sclerosis (PwMS) compared with healthy controls (HC). Methods: We gathered data from two neurology referral centers on PwMS and HC. Neurological and ophthalmological assessments,… Read more »